Reproductive System

Reproductive System

Summarize

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Epidemiological

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Etiology & Risk Factors

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Classification & Staging

 orchis

 

Cancer types

 

 

 

50. Acute lymphoblastic leukemia (ALL)
50.  germinoma
50.  hodgkin lymphoma
50.  non-Hodgkin lymphoma
50.  sarcoma
50.  carcinoma of testis

Cancer treated with whole body irradiation (TBI) prior to stem cell transplantation

 

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Type of cancer

 

 

 

 

50. Acute lymphoblastic leukemia (ALL)
50.  germinoma
50.  hodgkin lymphoma
50.  oophoroma
50.  embryoma of kidney
50. Cancer treated with whole body irradiation (TBI) prior to stem cell transplantation

 

 

Reproduction and reproduction

Fertility risk factors

 

50. The boy was given radiotherapy to his testicles
50. In girls, radiotherapy is used to treat the pelvis, including the ovaries and uterus
50. Radiation therapy is given to the hypothalamus or a region near it
50. Whole body irradiation (TBI) prior to stem cell transplantation
50. Chemotherapy with alkylating agents such as cisplatin, cyclophosphamide, busulfan, lomustine and pucacin
50. Surgery, such as the removal of testicles, ovaries or abdominal lymph nodes

 

Clinical Manifestations

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 S&S

 

50. Irregular or absent periods
50.  hot flash
50.  night sweat
50.  sleep problems
50.  emotion changes
50.  Decreased libido
50. Vaginal dryness
50. Can't get pregnant
50. Sexual characteristics, such as breast development, fullness of subcutaneous fat, and growth of pubic and leg hair, do not occur during puberty
50. Osteoporosis (easy to fracture)

 

 

        If your child has any of these problems, please consult your child's doctor.

Clinical Department

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Examination & Diagnosis

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Clinical Management

 orchis

 

 therapeutic tool

 

 

 

Surgery, such as the removal of a testicle, part of the prostate or lymph nodes in the abdomen

Chemotherapy with alkylating agents, such as cyclophosphamide, dacarbazine, pucacin and ifosfamide

Radiation therapy is given to the abdomen, pelvis or hypothalamus of the brain

Whole body irradiation (TBI) prior to stem cell transplantation

 

 

Possible health problems

 

Low sperm count: A zero or low sperm count can be temporary or permanent, depending on the radiation dose and schedule, the body area treated and the age at which the treatment is given.

Infertility: inability to have children.

Reversible ejaculation: At the time of orgasm, little or no semen is released from the penis.

 

 

        After chemotherapy or radiation therapy, the body's ability to produce sperm may recover over time.

 

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 therapeutic tool

 

 

 

 

The surgery involves removing one or both ovaries.

Chemotherapy with alkylating agents, such as cyclophosphamide, methchloramine, cisplatin, ifosfamide, lomustine, busulfan, and especially pucacin.

Radiation therapy to the abdomen, pelvis or lower back. For those who have recovered from radiation to the abdomen, damage to the ovaries depends on the dose of radiation, the age at which the treatment was given and whether all or part of the abdomen was exposed to radiation.

Radiation therapy to the abdomen or pelvis and alkylating agents.

Radiation therapy is located in the area of the brain near the hypothalamus.

Whole body irradiation (TBI) before stem cell transplantation.

 

 

 health issue

 

 

Premature menopause, especially in women who have had an oophorectomy or who are receiving both alkylating agents and abdominal radiotherapy

Changes in menstruation

Infertility (inability to conceive)

 delayed adolescence

 

 

        Ovarian function may change over time after chemotherapy.

 

Reproduction and reproduction

Long-term effects of late pregnancy

 

 hypertension

Pregnancy diabetes

 anemia

Miscarriage or stillbirth

 LBWI

 premature birth

 C-sect

Abnormal fetal position at delivery (e.g. breech or footling)

 

 

 intervention means

 

For patients who have entered puberty, freeze eggs or sperm before cancer treatment

Testicular sperm (a small amount of tissue containing sperm is taken from the testicles)

Intracytoplasmic sperm injection (ICSI) (one egg is fertilized with a single sperm, which is injected into the egg outside the body)

In vitro fertilisation (IVF) (where eggs and sperm are placed in a container so that the sperm has a chance to enter the egg)

 

 

The effects on future generations

 

        Children of childhood cancer survivors do not appear to have an increased risk of birth defects, genetic diseases or cancer.

Prognosis

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Follow-up & Review

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Daily Care

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Cutting-edge therapeutic and clinical Trials

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References

 data source ：

 

PDQ® Pediatric Treatment Editorial Board. PDQ Late Effects of Treatment for Childhood Cancer. Bethesda, MD: National Cancer Institute. Website: https://www.cancer.gov/types/childhood-cancers/late-effects-pdq. Date accessed: July 24,2018. [PMID: 26389365]

 

 

 

        Translated by Qian Yueping (Senior Manager of Medical Device Industry, Medical Clinical Affairs Department, PhD in Biology)

Audit specialists

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