Chordo-Epithelioma

Chordo-Epithelioma

Summarize

Chordoma is a very rare bone tumor that can form anywhere along the spine from the base of the skull to the coccyx. In children and adolescents, chordomas are more likely to occur at the base of the skull, making it difficult to remove them completely surgically.

        Childhood chordoma is associated with tuberous sclerosis, a genetic disorder that causes benign tumors (not cancer) to form in the kidneys, brain, eyes, heart, lungs and skin.

Epidemiological

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Etiology & Risk Factors

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Classification & Staging

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Clinical Manifestations

Cord tumors can cause any of the following symptoms and signs. If your child has any of these symptoms or signs, contact a pediatrician:

50.  headache
50. Neck or back pain
50. There are double images when looking at things
50. Facial muscle paralysis
50. Numbness, tingling or decreased muscle strength in the arms and legs
50. Changes in bowel or bladder habits

        In addition to chordoma, other diseases can cause the same signs and symptoms.

        Chordomas can recur, usually in the same location, but sometimes in other parts of the bone or lungs.

Clinical Department

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Examination & Diagnosis

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Clinical Management

For information on the treatments listed below, see the treatment overview section above.

        Children with chordoma are usually treated by surgically removing as much of the tumor as possible, followed by radiation therapy. Radiation therapy can be used with proton beam radiation therapy.

        Children with recurrent chordoma may consider participating in clinical trials to test for changes in genes in the patient's tumor samples. Targeted therapy may be administered based on the type of gene change. Patients with SMARCB1 gene changes may consider tazemetostat treatment in relevant clinical trials.

Prognosis

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Follow-up & Review

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Daily Care

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Cutting-edge therapeutic and clinical Trials

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References

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Audit specialists

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