Intraocular melanoma originates in the middle layer of the eye wall. The outer layer consists of the white sclera and the cornea in front of the eyeball. The inner layer is a neural tissue known as the retina, which senses light and transmits images to the brain via the optic nerve. The middle layer, known as the uvea, is the primary site of melanoma development, comprising three main parts: the iris, the ciliary body, and the choroid.
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Any of the following factors can increase the risk of intraocular melanoma:
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For information on the treatments listed below, see the treatment overview section above.
Treatment of intraocular melanoma in children is similar to that in adults and may include the following:
Children with recurrent intraocular melanoma may be considered for clinical trials to test whether the genes in the patient's tumor samples have changed. Targeted therapy may be given based on the type of gene change.
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